A group of experts from several universities, who conducted a study published in the journal Science Advances on May 3, 2024, made an extremely important discovery for health. Researchers have found that a human habit, early smoking, leads to an accelerated aging effect and later premature death.
The findings by doctors from Peking and Huazhong Universities, China and Oxford, UK, indicate that reducing early exposure to tobacco is crucial to improving healthy ageing, as it significantly influences biological aging and interacts with various factors such as age, sex, deprivation and diet , according to Medical News.
Biological aging is a complex process characterized by cumulative cellular changes that progressively impair the integrity of tissues and organs. This leads to increased vulnerability to morbidity and premature mortality and imposes a substantial financial burden on health systems.
The miracle paint invented, unprecedented in the world: You put it on the house and you don’t need air conditioning anymore VIDEO
Recent reviews have highlighted the importance of quantifying biological age (BA) through various biomarkers to accurately predict health outcomes. Early environmental exposures, particularly tobacco exposure, have been identified as significant risk factors for adverse health effects in adulthood.
Lose weight quickly and easily with the help of Lipovon. Natural ingredients. Immediate delivery.
This study examined the association between early tobacco exposure and biological aging in adults using multiple biomarkers, including telomere length (TL) and composite clinical parameter algorithms.
In addition, it investigated the combined impact of genetic susceptibility and tobacco exposure on the acceleration of biological aging, with the aim of providing insights for preventive and therapeutic interventions aimed at healthy aging.
Doctors warning. The condition that can kill you: In 40 minutes you can have a heart attack or stroke VIDEO
The study used data from UK Biobank (Great Britain), a population-based cohort study of approximately half a million participants aged 37 to 73 years enrolled between 2006 and 2010. After exclusions, there were including a total of 276,259 participants.
Early exposure to tobacco, including in utero exposure and age of smoking initiation, was assessed by self-reported questionnaires. BA was determined using Klemera-Doubal Biological Age (KDM-BA) and Phenotypic Age (PhenoAge) algorithms validated with NHANES data.
Further statistical analysis revealed strong associations between early tobacco exposure and accelerated biological aging. Remarkably, subjects with in utero exposure demonstrated significant increases in both KDM-BA and PhenoAge acceleration, coupled with a remarkable reduction in TL. Specifically, in utero exposure was linked to a 0.26-year increase in KDM-BA acceleration, a 0.49-year increase in PhenoAge acceleration, and a 5.34% decrease in TL.
Surprisingly, a drink is good for the heart and brain: It contains a miraculous substance for the human body
In addition, a clear dose-response trend emerged for age of smoking initiation, with earlier initiation correlating with more pronounced acceleration of biological markers of aging.
For example, childhood tobacco exposure was associated with a 0.88-year increase in KDM-BA acceleration, a 2.51-year increase in PhenoAge acceleration, and a 10.53% decrease in TL, compared with those who never smokes.
This study investigates how early tobacco exposure, spanning the fetal, childhood, and adolescent periods, relates to higher rates of biological aging in adulthood.
Smoking leads to accelerated aging and an increased risk of premature death from diseases such as cancer and serious cardiovascular and lung diseases.
Add comment
Tags: Alarming discovery Habit practiced leads rapid aging premature death
-
